Mitosis Skill Tree: Costs, Branches and Upgrade Choices

Open SKILL TREE at the top of the main screen. Hover over or select a node to read its full name, effect, Token price, and ownership status. Short node labels can differ from their descriptions: Tokens I is Token Power I, for example.

Follow CLICK TO BUY, or tap the selected node again when the prompt says TAP AGAIN TO BUY. A purchased node shows OWNED. NOT ENOUGH TOKENS means you need a larger balance for that purchase. Use the right-side + / − controls to zoom and CLOSE at the bottom to leave.

The directory covers known nodes and their available properties. Search by a name or alias, and expand More details for additional fields and connections. Prices belong to the conditions listed with each entry; abbreviated prices such as 1.0K and 1.1K Tokens retain their displayed precision.

For the central skill's purchase and AUTO controls, follow the Auto-Split guide.

• Rebuilding production after rebirth: choose Quick Start. For 29 Tokens, each run starts with a 3.2-second split cooldown and 40-ball capacity. This makes it a useful early choice when repeatedly rebuilding speed and capacity is your main bottleneck. Ball Value still starts at level 0 after rebirth. See rebirth resets for what carries over, or basic upgrades for improving the run further.
• Increasing ball value: choose Value I / Ball Value I. Its initial branch price is 27 Tokens, and it doubles ball value. This is the more direct choice when your immediate goal is to raise what each ball is worth rather than improve the starting setup.
• Fitting another card: choose Slot 4 / Fourth Slot. For 30 Tokens, it adds one card slot, taking a three-slot setup to four. Prioritize it when you have another useful card ready to include. Continue with card management to arrange your loadout.
• Improving the money bonus per token: choose Tokens I / Token Power I. It costs 170 Tokens and changes the bonus from +2% to +2.5% per token. Its purpose differs from the cheaper production upgrades, so save for it when that bonus is your priority. Use the Tokens guide to weigh skill purchases against card spending.

Big Sells I, labeled Sell I on the tree, doubles sell earnings. Ball Value I doubles ball value. Keep those targets distinct when comparing descriptions; do not treat them as interchangeable effects.

For later purchases, Rebirth I / Token Boost I costs 360 Tokens and states 50% more tokens. Moles I / Mole Hills costs 950 Tokens and states 2× moles. Token Boost I targets token quantity, while Token Power I improves the money bonus per token.

Use these purchase-to-reveal connections to find your next node. They describe how branches open; check the selected node's current purchase prompt before spending.

For the two-ball branch, continue to the start chip instructions. For the gold entrance, see how to open Mutation Upgrades.

1. Open SKILL TREE. After purchasing Quick Start, find 2 BALLS above-right of it. Look for the red-and-green pair of balls.
2. Select the node to read 2-Ball Start, then purchase it for 250 Tokens using the displayed prompt.
3. Choose CLOSE to return to the main screen. The unlock message points to the start chip on SPLIT.
4. Use that small chip at the upper-right edge of SPLIT to switch between ×2 and ×1. Select ×2 to start new boards with two balls, or ×1 to start with one.

The small chip sets the next board's starting count. The larger count above SPLIT shows how many balls are on the current board. Changing the start setting does not describe your current batch size.

Purchasing 2-Ball Start reveals 4 BALLS / 4-Ball Start above it. Its displayed price is 3.5K Tokens, and its description says you start with four balls.

After purchasing Quick Start, find the gold hexagonal Mutations node above-left of it. Select the entrance marked OPEN / CLICK TO OPEN to enter the separate mutation upgrade tree. Upgrades inside that tree use Tokens.

To identify a ball's mutation, classification, or known effect, use the Mutation Index.